1. How to stable the end length of chromosome?
(A) Topmere
(B) Endmere
(C) Telomere
(D) Centromere
(E) Bottomere

2. What is the coding strand? (A) The DNA strand whose base sequence corresponds to the base sequence of the RNA transcript produced (B) The RNA strand whose base sequence corresponds to the base sequence of the RNA transcript produced (C) The DNA strand whose base sequence complements to the base sequence of the RNA transcript produced (D) The DNA strand whose base sequence complements to the base sequence of the RNA transcript produced (E) The cDNA strand whose base sequence complements to the base sequence of the RNA transcript produced

3. Prion is composite of what macromolecule(s)? (A) RNA (B) DNA (C) cDNA (D) Protein (E) Lipid

4. In a eukaryotic cell, when or where is the packing ratio of DNA being the highest? (A) DNA replication (B) Mitosis (C) Apoptosis (D) Euchromatin region (E) RNA transcription initiation

5. The features of a plasmid expression vector usually not including _____? (A) Replication origin (B) Antibiotic resistance gene (C) Multiple cloning site (D) Promoter (E) Telomere ?

6. In animal cells, which of the following organelles contains genetic material in addition to nucleus? (A) Golgi apparatus (B) Mitochondrion (C) Chloroplast (D) Endoplasmic reticulum (E) Lysosome

7. Which of the statements about nucleus is NOT CORRECT? (A) Structures as a double-membrane compartment (B) Containing bulk of genome (C) RNA transcription (D) DNA maintenance (E) Exosome secretion

8. What is the primary role of DNA methylation in DNA replication of E. coli? (A) The hemimethylated origin region of DNA replication are inactive for initiation (B) The methylated CpG island is important for DNA initiation of DNA replication (C) The methylation of DNA is important for restriction-modification systems (D) The methylation of origin region containing GATC sequences is important for the regulation of DNA priming (E) DNA methylation has no function in DNA replication

9. The central dogma of molecular biology including two processes: transcription and _____? (A) Reverse transcription (B) Degradation (C) Replication (D) Translation (E) Reverse replication

10. Which of the following ones does NOT happen in mRNA processing? (A) Splicing (B) Editing (C) Polyadenylation (D) All of the above (E) None of the above

11. Which of the following statements about the CRISPER-Cas9 is wrong? (A) One of the great genome-editing tools (B) A naturally occurred system in yeast (C) A guide RNA is needed (D) With the ability to change an organism's DNA (E) More efficient than other existing genome-editing methods

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