111. 有關合併症與高血壓治療首選之配對，下列何者正確？
(A) 糖尿病 (DM)－Amlodipine
(B) 上心室心搏過速 (PSVT)－Irbesartan
(C) 冠狀動脈心臟疾病 (CAD)－Bisoprolol
(D) 慢性腎臟疾病 (CKD)－Verapamil

112. Mr. Wu is a 71 year-old male who has worked as a painter for 50 years. He presented to his primary care doctor with complaints of hematuria and urinary urgency. He was referred to a urologist for cystoscopy. Office cystoscopy found a lesion in the bladder and he underwent a subsequent TURBT (transurethral resection of the bladder tumor) that revealed Tis (in situ), nonmuscle invasive urothelial carcinoma (UC). What is the best treatment option for Mr. Wu? (A) Intravesical Bacillus Calmette-Guerin (BCG) (B) Intravesical Valrubicin (C) Intravesical Mitomycin (D) No therapy is needed at this time

113. LB is a 25 year-old female with AML day 24 s/p 7+3 induction (anthracycline plus cytarabine). Her course has been complicated by culture negative febrile neutropenia with chest x-ray findings (day 20) suggestive of pneumonia. She has received cefepime since day 20. She has been afebrile for 72 hours and has now recovered her neutrophil count. Your leukemia team would like to know when it would be appropriate to discontinue antibacterials. Which of the following is most appropriate response? (A) LB should stop cefepime since neutropenia has resolved and has been afebrile for at least 2 days (B) LB has received an adequate course for pneumonia therefore cefepime can be discontinued (C) LB has received an adequate course for pneumonia and cefepime can be switched to levofloxacin prophylaxis (D) LB has not received an adequate course for pneumonia but can be de-escalated to oral stepdown therapy to complete her treatment

114. 下列敘述何者正確？ (A)steady-state vancomycin trough concentration 建議維持在＜10 μg/mL，避免毒性發生 (B)vancomycin 屬於 concentration-dependent 抗生素 (C)建議在給與第二次 vancomycin 劑量前進行 steady-state trough concentration 監測 (D)vancomycin 使用時，須定期監測病人的 WBC、體溫及 serum creatinine

115. 有關 phenytoin 之敘述，下列何者錯誤？ (A)眼球震顫及步態不穩為其副作用 (B)齒齦增生及多毛症為其副作用 (C)長期使用不會影響骨質 (D)其代謝為非線性藥動學

116. 下列何者不屬於 inodilators？ (A) Milrinone (B) Norepinephrine (C) Dobutamine (D) Levosimendan

117. 40 歲肝腎功能正常男性，感染 Staphylococcus aureus 骨髓炎，下列治療何者最不適當？ (A) methicillin-susceptible，使用 oxacillin 2 g Q4H IV (B) methicillin-resistant，使用 vancomycin 1 g Q12H IV (C) methicillin-resistant，使用 rifampin 600 mg QD PO (D) methicillin-resistant，使用 linezolid 600 mg Q12H PO

118. 15 歲學生，有輕度氣喘 5 年，近 1 年內平均每 3～4 個月需要使用一次 inhaled albuterol。 規劃參加韻律舞課，每週 2 次、每次 1 小時。運動前 15 分鐘單獨使用下列何種吸入劑最適當？ (A) salmeterol (B) salbutamol (C) budesonide (D) tiotropium

119. 利尿劑用於心衰竭病人的主要目的為何？ (A) 增加心跳以提高心輸出量 (B) 降低 afterload 以減少心臟負擔 (C) 降低 preload 以減少心臟負擔 (D) 增強心收縮力以提高心輸出量

複選題120. 有關靜脈注射鐵劑之敘述，下列何者正確？ (A) 須與 fluoroquinolone、MgO 間隔 2 小時給藥 (B) 可能導致輸注反應，如低血壓 (C) 可能導致糞便顏色變黑 (D) 空腹給藥時吸收較佳

121. 70 歲男性，因高血壓及慢性腎臟病（CKD）長期使用 furosemide、valsartan 與 amlodipine，腎功能穩定。今發現血中 K+ 5.6 mmol/L（參考值 3.5～5.0），但無任何不適，心電圖正常。下列何者與其血鉀異常的關連性最低？① furosemide ② valsartan ③ amlodipine ④ CKD ⑤ 病人表示最近攝取較多水果與果汁 (A) ①, ③ (B) ④, ⑤ (C) ①, ⑤ (D) ②, ④

113年 - 2024 藥學專業題庫(選擇題)101-141#119331

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113年 - 2024 藥學專業題庫(選擇題)51-100#119329