17. Which statement about sickle-cell disease is false?(A) The sickle-cell hemoglobin molecule contains an amino acid substitution.(B) Individuals who are heterozygous for the sickle-cellallele cannot make hemoglobin.(C) The red blood cells of an individual with sickle-cell disease distort and elongate.(D) The hemoglobin molecules of an individual with sickle-cell disease clump together.(E) All of above are true.