19.牛運輸熱肺泡腔所見的燕麥形細胞(oat-shaped cell),是下列何種細胞受細菌毒素作用所致?
(A)肺泡壁細胞
(B)嗜中性球
(C)淋巴球
(D)肺泡巨噬細胞與淋巴球
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統計: A(343), B(1266), C(85), D(1240), E(0) #1587825
統計: A(343), B(1266), C(85), D(1240), E(0) #1587825
詳解 (共 7 筆)
#3767651

B, Note a large irregular area of necrosis (N) of the pulmonary parenchyma. Typically, these necrotic areas are surrounded by an outer dense layer of inflammatory cells (arrows). The interlobular septa are distended (arrowheads). Inset (bottom right corner) shows the typical elongated and basophilic appearance of degenerated neutrophils known as oat cells. H&E stain.
病理第六版p531
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#7393116
Oat-shaped cell 是什麼?
本質
受到細菌毒素(Leukotoxin)作用後的:
退化性嗜中性球(Degenerate neutrophils)
顯微鏡特徵
• 細胞核拉長
• 核染色質濃縮
• 外觀呈細長橢圓形
• 類似燕麥粒(oat grain)
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#7440757
APP跟Mannheimia haemolytica(牛運輸熱主要病原之一)的病變很相似(纖維素性胸膜肺炎)
而且也會出現燕麥細胞(oat-shaped cell)
但APP的病灶主要是在膈葉 (隔夜燕麥...)
Mannheimia haemolytica主要分布於尖、心葉
ㅤㅤ
加碼:Mycoplasma mycoides ssp. mycoides (牛接觸性胸膜肺炎)也會導致纖維素性胸膜肺炎,但主要病變在膈葉,且通常呈單側性分佈(考過)
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