12. What is the name of this molecule?

(A) α-D-ribopyranose
(B) α-L-ribopyranose
(C) β-D-ribopyranose
(D) β-L-ribopyranose
(E) none of above. 

13. Which one is the cleavage site of Phospholipases D?

14. In a sample of double-stranded DNA containing 32% cytosine, the percentage of adenine would be (A) 32% (B) 18% (C) 68% (D) 36% (E) Insufficient information to answer question.

15. Which of the following supposedly has the greatest affinity to the proline racemase? (that catalyzes the following reaction) A transition state analog:(A) L-Proline (B) D-Proline (C) The planar transition state (D) Pyrrole-2-carboxylate (E) Proton.

16. A plot of 1/v vs. 1/[S] for an enzyme catalyzed reaction gave a line with an equation of 1/v = 0.4/[S] + 0.2. The same enzyme with an inhibitor present gave a line with an equation of 1/v = 0.4/[S] + 0.8. Which of the following statements is true? (A) the type of inhibition is competitive (B) the type of inhibition is noncompetitive (C) the type of inhibition is uncompetitive (D) the Km with the inhibitor present has decreased (E) None of the above.

17. We have two enzymes maltose phosphorylase and sucrose phosphorylase catalyzing the following reactions: With the presence of unlabeled G-1-P and sucrose phosphorylase in an isotope-labeled 32P； solution, we found the "P" on G-1-P can also be isotope-labeled after some time. However, maltose phosphorylase cannot do the same. Which of following is true: (A) Sucrose phosphorylase catalyzes a reaction following double-displacement mechanism (B) Sucrose phosphorylase catalyzes a reaction requiring the formation of tertiary complexes (C) Maltose phosphorylase catalyzes a reaction following what is called "Ping-Pong mechanism" (D) Maltose phosphorylase catalyzes a reaction where enzyme is covalently modified during the catalysis though the modification occurs only transiently (E) NAD+-dependent dehydrogenases use a random single-displacement catalytic mechanism

18. About Near Attack Conformation (NAC), which of the following is NOT true? (A) Computer simulations find that the chance of NAC to form in the enzyme active site can be 300,000 times larger than that of NAC in the absence of the enzyme (B) the energy difference of E.NAC→E.X+ is smaller than that of NAC→X+ where X+ means the transition state (C) The enzymatic catalysis benefits from lowering the energy barrier of S→NAC (D) The transition state analog has a configuration closer to the transition state than the NAC (E) Both the catalyzed and uncatalyzed reactions require the formation of NAC

19. Which of the following will NOT change the Phosphorylases' activity? The energy level in our bodies. (A) Glucose-6-P (B) Caffeine (C) AMP (D) ADP (E) ATP

20. About hemoglobin, which of the following is NOT true? (A) It forms different intra/intermolecular hydrogen-bonding patterns in the 'T' and 'R' forms (B) It demonstrates a mixed KNF and MWC model (C) It binds oxygen weaker than myoglobin below the P50. (D) It is regulated by pH values (E) It transfers CO₂ to the lung via the oxygen binding pocket.

21. The following figure shows how Cyclic AMP-dependent protein kinase (PKA) is regulated. The catalytic subunits are controlled by: (A) allosteric control (B) zymogen control (C) covalent modification (D) intrasteric control (E) product inhibition.

22. Insulin in the bloodstream is a response to increased blood glucose, and: (A) stimulates gluconeogenesis, (B) inhibits glycolysis, (C) stimulates glycogen synthesis in muscle and liver, (D) stimulates glycogen breakdown in liver, (E) inhibits phosphoprotein phosphatase-1.

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