24. What is the function of biotin in metabolism?
(A) Streptavidin binding
(B) Transfer of oxidized nitrogen
(C) Transfer of reduced nitrogen
(D) Transfer of oxidized carbon
(E) Transfer of reduced carbon

25. Which of the amino acid is NOT glucogenic? (A) Isoleucine (B) Leucine (C) Arginine (D) Tryptophan (E) Aspartatic acid

26. Which of the following enzymes is not involved in synthesis of 22:6(n-3) fatty acid from 18:3(n-3) fatty acid? (A) Δ⁴ desaturase (B) Δ⁶ desaturase (C) Δ⁵ desaturase (D) elongase

27. Which of the following statements is true? (A) Chylomicron remnants can be uptaken by the liver through ApoB-100 binding to LDL-receptor (B) HDL contains ApoB-100 but not Apo-B48 (C) Apo-Al is a major protein HDL and an activator of lecithin:cholesterol acyl-transferase (D) Apo-CII is an activator of hormone sensitive lipase (E) Low density lipoprotein (LDL) can be converted to intermediate-density lipoproteins(IDL) by lipoprotein lipase

28. Which of the following enzymes is the major target of aspirin (a nonsteroidal anti-inflammatory drug)? (A) Acyl-CoA synthetase (B) Cyclooxygenase (C) HMG-CoA reductase (D) HMG-CoA synthase (E) Lipoxygenase

29. Lipoprotein lipase deficiency leads to: (A) hyperglycemia (B) hypoglycemia (C) ketonemia (D) hypertriglyceridemia (E) hypercholesterolemia

30. Which of the following enzymes are responsible for the synthesis of palmitate from acetyl-CoA? (A) HMG-CoA synthase and HMG-CoA reductase (B) Acetyl-CoA carboxylase and Fatty acid synthase (C) Acyl-CoA synthetase and Acyl-CoA dehydrogenase (D) Phosphoenolpyruvate carboxykinase and Pyruvate carboxylase (E) Δ⁹-desaturase and elongase

31. Which following enzyme only has one direction reaction? (A) enolase (B) glutamate dehydrogenase (C) aminotransferase (D) glutaminase (E) Serine hdroxymethyltransferase.

32. What material communication happens between liver and muscle in Cori cycle? (A) HDL and VLDL (B) HDL and LDL (C) glucose and lactate (D) fat and cholesterol (E) VLDL and alanine.

33. Which activity of following proteins will be reduced by phosphorylation? (A) phosphorylase kinase (B) 6-phosphofructokinase-2 (C) Inhibitor-1 for protein phosphatase 1 (D) 6-phosphofructokinase-1 (E) PKB/Akt.

34. What two modifications are required for serotonin biosynthesis from tryptophan? (A) hydroxylation and decarboxylation (B) adenosylation and methylation (C) dehydrogenation and phosphorylation (D) hydrogenation and phosphorylation (E) decarboxylation and hydrogenation.

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