29. Which one below is not the component of membrane?
(A) Lipid
(B) Protein
(C) Cholesterol
(D) Sterol
(E) None of above all

30. Phosphatidylinositol (PtdIns) is a small lipid to regulate diverse biological function. The activity/function of PtdIns can be modulated by kinases and phosphatases. The kinases-mediated phosphorylation is happening on hydroxyl positions of the inositol ring. Which position below is not the site for phosphorylation? (A) 3 hydroxyl position (B) 4 hydroxyl position (C) 5 hydroxyl position (D) 3 and 4 hydroxyl positions (E) 6 hydroxyl position

31. Which one below is not membrane-bound organelles/vesicles in cells? (A) Giant unilamella vesicles (GUV) (B) Mitochondria (C) Late endosome (D) Chloroplast (E) Lysosome

32. Which one below is not the feature of signal-transducing systems? (A) Specificity (B) Desensitization (C) Integration (D) Amplification (E) None of above all

33. In G-protein coupled receptors what subunit binds to GTP and has GTPase activity? (A) Alpha (B) Beta (C) Gamma (D) Delta (E) Epsilon

34. All G-protein coupled receptors are? (A) 1 membrane-spanning receptors (B) 5 membrane-spanning receptors (C) 7 membrane-spanning receptors (D) 10 membrane-spanning receptors (E) 13 membrane-spanning receptors

35. What enzyme converts ATP into cAMP? (A) ATPase (B) Cyclic nucleotide phosphodiesterase (C) Adenylate cyclase (D) Serine kinase (E) All of the above

36. Phosphatidylinositol 4,5-bisphosphate (PIP2) is cleaved into what secondary messengers? (A) IP3 (inositol triphosphate) and DAG (diacylglycerol). (B) IP3 and NO (nitric oxide) (C) Calcium and DAG (D) NO and DAG (E) All of the above

37. In protein translation, release factors are required in which stage: (A) activation of amino acids. (B) initiation. (C) elongation. (D) termination. (E) protein folding.

38. For targeting nuclear proteins, nuclear localization sequences are recognized by: (A) SRP. (B) proteasome. (C) Ion channels. (D) microtubule. (E) importin.

39. In genome, a silent mutation in protein coding region will lead to: (A) a wrong amino acid incorporated into protein. (B) premature termination. (C) no change of amino acid sequence. (D) a frame shift. (E) initiation failure.

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