36. In terms of chemical properties, which of the following amino acids is lysine most similar to?
(A) Arginine
(B) Phenylalanine
(C) Serine
(D) Aspartic acid
(E) Proline

37. Chymotrypsin preferentially cleaves after amino acids tryptophan, tyrosine, and phenylalanine in a protein. To a lesser extent, it may also cleave after leucine, methionine, and histidine. Which of the following peptides is NOT a product of chymotrypsin? (A) RSIAF (B) NWPQALPSVL (C) QIAM (D) EPDTDW (E) SIAFSR

複選題38. SDS-PAGE is a method in which proteins coated with negatively charged detergent SDS are separated along a gel matrix in the presence of an electric field. The method separates proteins based on relative molecular weights of proteins. Which of the following statements about SDS-PAGE is TRUE? (A) Larger proteins bind more negatively charged SDS and run faster (B) Larger proteins run slower because they are heavier (C) Larger proteins run slower because they face a greater resistance (D) Proteins run from anode to cathode (E) Larger proteins separate better in a higher percentage SDS-PAGE gel

39. The figure on the right summarizes the effects of pH on oxygen binding affinity of hemoglobin (the Bohr effects). Based on the figure, which of the following statement is TRUE? (A) Curve A represents binding in the highest pH (B) Curve B represents binding in the highest pH (C) Curve C represents binding in the highest pH (D) Curve A has the highest affinity (E) Curve A bind the highest amount of oxygen for a given oxygen pressure

40. Which of the following statements about isoelectric point is TRUE? (A) An isoelectric point is the pH where a molecule has equal negative and positive charges (B) Proteins have isoelectric points but amino acids do not (C) Positive charges of a protein increase as pH increases (D) At the isoelectric point, a molecule moves to the anode in an electric field (E) Since proteins carry zero charges at isoelectric points, electrophoresis cannot separate different proteins based on isoelectric points

41. Which of the following structure is the correct Fischer projection of       D-galactose      ? (A)(B)(C)(D)(E)

42. Which of the following monosaccharide is not a component of the carbohydrate moiety of proteoglycans and glycoproteins? (A) Galactose (B) Glucose (C) Mannose (D) Ribose (E) Xylose

43. How many molecules of ATP are invested in the preparatory phase and "harvested" in the pay-off phase of glycolysis from one molecule of glucose, respectively? (A) 2, 4 (B) 4, 2 (C) 2, 2 (D) 2, 32 (E) 2, 6

44. Which small RNA is not involved in gene silencing? (A) miRNA (B) snRNA (C) piRNA (D) siRNA (E) None of the above.

45. Which of the following coenzymes is/are required for citric acid cycle? (1) Coenzyme A, (2) Flavin adenine dinucleotide (FAD), (3) Biotin, (4) Nicotinamide adenine dinucleotide (A) 1,3,4 (B) 1, 2, 4 (C) 2,4 (D) 1,2,3 (E) 1, 2, 3, 4

46. The Km (Michaelis constant) of an enzyme for a substrate is defined operationally as (A) half the substrate concentration at which the reaction rate is maximal (B) the substrate concentration at which the reaction rate is half maximal (C) the dissociation constant of the enzyme substrate complex (D) the dissociation constant of the enzymeproduct complex (E) the rate constant of the reaction at saturation

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