6. What deficiency would lead to the symptom of pernicious anemia?
(A) Vitamin B12
(B) Vitamin C
(C) Biotin
(D) Vitamin E
(E) Calcium cation

7. Which enzyme controls free guanine and hypoxanthine salvage? (A) Adenosine phosphoribosyltransferase (B) Hypoxanthine-guanine phosphoribosyltransferase (C) Purine aminotransferase (D) Purine amidotransferase (E) Ribonucleotide reductase

8. How much free ammonia would one AMP catabolism lead to? (A) 2 (B) 3 (C) 4 (D) 5 (E) 6

9. What type of secondary structure shown below is? (A) Type I α turn (B) Type II α turn (C) Type I β turn (D) Type II β turn (E) Type III β turn

10. According to the Bohr effect, given the following graph, how much more O2 can be delivered by hemoglobin to the peripheral tissue when the peripheral tissue elevates the concentration of CO2?  (A) 20% (B) 30% (C) 35% (D) 40% (E) 45%

11. Which amino acid catabolism can lead to the formation of α-ketoadipate? (A) Methionine, Histidine (B) Glycine, Cysteine (C) Leucine, Serine (D) Lysine, Tryptophan (E) Valine, Phenylalanine

12. Which of the following statements about fatty acids is correct? (A) Fatty acids are primarily stored in the body as triglycerides in muscle tissue. (B) Fatty acids with a higher number of double bonds tend to be more hydrophobic. (C) Omega-3 fatty acids are known to be beneficial for cardiovascular health. (D) Fatty acids are not involved in energy metabolism under normal conditions. (E) Short-chain fatty acids are typically found in significant amounts in dietary fats.

13. Cholesterol is synthesized from: (A) acetyl-CoA (B) malate (C) oxalate (D) lipoic acid (E) choline

14. The precursor of paracrine hormones such as prostaglandins is: (A) Palmitate (B) arachidonate (C) oleate (D) ceramide (E) steroid

15. Ketone bodies are used as fuels in all tissues except liver, which lacks: (A) β-ketoacyl-CoA transferase (B) HMG-CoA synthase (C) HMG-CoA reductase (D) HMG-CoA lyase (E) thiolase

16. Acyl carrier protein (ACP) is an important part of fatty acid biosynthesis because: (A) ACP binds the final product of fatty acid synthase to transport it to other places in the cell. (B) ACP connects the acetyl-CoA carboxylase with fatty acyl chain. (C) ACP covalently links with the acyl group from one active site to another in sequence. (D) ACP is essential only for the thioesterase activity that releases the product fatty acid from the enzyme. (E) ACP provides a way to store pantothenic acid when abundant so it is available during times when the amount of this vitamin in the diet is inadequate.

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