22. Which statement best explains why eukaryotic enhancers can regulate transcription from promoters located thousands of base pairs away?
(A) Enhancers encode small RNAs that migrate to the promoter
(B) Enhancer–promoter communication occurs via DNA looping mediated by coactivator proteins
(C) Enhancers move within the nucleus to physically bind the promoter
(D) Enhancers are transcribed into mRNA that recruits RNA polymerase II